Thursday, July 14, 2011

Difference between Thrombus and Embolus

Feature
Thrombus
Embolus
Definition
A thrombus is a firm mass of blood constituents(e.g. platelets,fibrin,and entrapped cellular elements) which developes within a circulatory system.
An embolus is a apart intravascular solid,liquid or gaseous mass that is supported by the body fluid to a site distant from its point of origin.
Source
Always formed from the constituents of streaming blood.




Nearly all emboli represent some part of a removed thrombus,hence the commonly used term thromboembolism.99% embolus are originated from thrombus(Thromboembolism).
Phase
Thrombus is a stationary solid mass that may obstruct blood flow.Attached to the vessel wall of the site of origin.
Freely floating solid/liquid/gaseous mass,not attached to the site of origin.
Location
Localised at the site of origin.
Disruption of certain thrombus causes embolism travel in the circulation and may obstract to a site distant from its point of origin.
Types
Anatomical
·         Cardiac
·         Arterial
·         Venous
·         Capillary
Morphological
·         Pale (platelet thrombus)
·         Red (RBC thrombus)
·         Mixed (intermittent layers)
Types of embolus
·         Systemic thromboembolus
·         Fat embolus
·         Air embolus
·         Amniotic fluid embolus
Effect
 Ø      Dependent on location and degree of     vascular occlusion.
 Ø      availability of collateral blood supply and susceptibility of area of supply to interruption of blood supply.
 Ø      Dependent on extent of disruption to the local circulation and susceptibility of the target organ or tissue to such disruption.
Example
Deep venous thrombus
Pulmonary embolus